ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis
نویسندگان
چکیده
منابع مشابه
ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis.
Very long-chain fatty acids (VLCFAs) exert a variety of cellular functions and are associated with numerous diseases. However, the precise pathway behind their elongation has remained elusive. Moreover, few regulatory mechanisms for VLCFAs synthesis have been identified. Elongases catalyze the first of four steps in the VLCFA elongation cycle; mammals have seven elongases (ELOVL1-7). In the pre...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2010
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1005572107